Article
HMG-CoA reductase expression in breast cancer is associated with a less aggressive phenotype and influenced by anthropometric factors.
International journal of cancer - 1 Sept 2008
Borgquist Signe, Djerbi Soraya, Pontén Fredrik, Anagnostaki Lola, Goldman Malin, Gaber Alexander, Manjer Jonas, Landberg Göran, Jirström Karin
Abstract excerpt
Although several studies have reported on the anti-tumoural properties exerted by 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoAR) inhibitors (statins), the in vivo expression of HMG-CoAR in human cancer has been considerably less investigated. In our study, we examined the immunohistoc...
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