Article
In vitro differential sensitivity of melanomas to phenothiazines is based on the presence of codon 600 BRAF mutation.
Molecular cancer therapeutics - 1 Jun 2008
Ikediobi Ogechi N, Reimers Mark, Durinck Steffen, Blower Paul E, Futreal Andrew P, Stratton Michael R, Weinstein John N
Abstract excerpt
The panel of 60 human cancer cell lines (the NCI-60) assembled by the National Cancer Institute for anticancer drug discovery is a widely used resource. We previously sequenced 24 cancer genes in those cell lines. Eleven of the genes were found to be mutated in three or more of the lines. Using a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.