Article
Aneuploidy related transcriptional changes in endometrial cancer link low expression of chromosome 15q genes to poor survival.
Oncotarget - 7 Feb 2017
Mauland Karen Klepsland, Wik Elisabeth, Hoivik Erling A, Kusonmano Kanthida, Halle Mari Kyllesø, Berg Anna, Haugland Hans Kristian, Øyan Anne Margrete, Kalland Karl-Henning, Stefansson Ingunn Marie, Akslen Lars A, Krakstad Camilla, Trovik Jone, Werner Henrica Maria Johanna, Salvesen Helga Birgitte
Abstract excerpt
Aneuploidy is a widely studied prognostic marker in endometrial cancer (EC), however, not implemented in clinical decision-making. It lacks validation in large prospective patient cohorts adjusted for currently standard applied prognostic markers, including estrogen/progesterone receptor status (ER/PR). Also, little is known about aneuploidy-related transcriptional alterations, relevant for understanding its role...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
