Article
Relationship between sex, shape, and substrate in hypertrophic cardiomyopathy.
American heart journal - 1 Jun 2008
Bos J Martijn, Theis Jeanne L, Tajik A Jamil, Gersh Bernard J, Ommen Steve R, Ackerman Michael J
Abstract excerpt
BACKGROUND: Hypertrophic cardiomyopathy (HCM) is a disease characterized by substantial genetic, morphologic, and prognostic heterogeneity. Recently, sex-related differences in HCM were reported, with women being older at diagnosis and exhibiting greater left ventricular outflow tract obstruction than men. We sought to evaluate the influence of sex on the HCM phenotype in a large cohort of unrelated patients with...
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