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Article

Does the genotype of hypertrophic cardiomyopathy impact the outcomes of septal myectomy?

The Journal of thoracic and cardiovascular surgery - 1 Aug 2026

Karadzha Anastasiia, Schaff Hartzell V, Sawma Tedy, Todd Austin, Geske Jeffrey, Dearani Joseph, Bos Martijn, Ackerman Michael, Ommen Steve, Maleszewski Joseph

Abstract excerpt

BACKGROUND: This study investigated the relationship between genetic profiles and clinical, pathologic, and surgical outcomes in patients undergoing septal myectomy for obstructive hypertrophic cardiomyopathy (oHCM). METHODS: Clinical, echocardiographic, and histopathologic data were compared across 3 groups: variant-positive (VP), variant of undetermined significance (VUS), and variant-negative (VN). RESULTS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42119720
DOI: 10.1016/j.jtcvs.2026.04.051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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