Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutation in the rel gene of Sorangium cellulosum affects morphological and physiological differentiation.

Molecular microbiology - 1 Jul 2008

Knauber Tina, Doss Sabrina D, Gerth Klaus, Perlova Olena, Müller Rolf, Treuner-Lange Anke

Abstract excerpt

Interruption of the (p)ppGpp synthetase gene (rel) of Sorangium cellulosum So ce56 resulted in loss of ppGpp accumulation after norvaline treatment during exponential growth phase. The rel mutant failed to produce wild-type levels of the polyketides chivosazol and etnangien in production media. In wild-type cells expression of the chivosazol biosynthetic operon can be significantly increased by norvaline or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Genetic Complementation Test

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ligases

Share to Macrolides

Share to Mutation

Share to Protein Structure, Tertiary

Share to Transcription, Genetic

Source

Identifiers

PMID: 18513216
DOI: 10.1111/j.1365-2958.2008.06285.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

Mutation in the rel gene of Sorangium cellulosum affects morphological and physiological differentiation.PMID 18513216Read ↗

Isolation and characterization of the epothilone biosynthetic gene cluster from Sorangium cellulosumSemantic proximity Read ↗

Influences of genetically perturbing synthesis of the typical yellow pigment on conidiation, cell wall integrity, stress tolerance, and cellulase production in Trichoderma reesei.Semantic proximity Read ↗

RelA-dependent (p)ppGpp production controls exoenzyme synthesis in Erwinia carotovora subsp. atroseptica.Semantic proximity Read ↗

Envoy, a PAS/LOV domain protein of Hypocrea jecorina (Anamorph Trichoderma reesei), modulates cellulase gene transcription in response to light.Semantic proximity Read ↗

A relaxed (rel) mutant of Streptomyces coelicolor A3(2) with a missing ribosomal protein lacks the ability to accumulate ppGpp, A-factor and prodigiosin.Semantic proximity Read ↗

Streptomyces clavuligerus relA-null mutants overproduce clavulanic acid and cephamycin C: negative regulation of secondary metabolism by (p)ppGpp.Semantic proximity Read ↗

Streptomyces relC mutants with an altered ribosomal protein ST-L11 and genetic analysis of a Streptomyces griseus relC mutant.Semantic proximity Read ↗

Regulation of cellulase expression, sporulation, and morphogenesis by velvet family proteins in Trichoderma reesei.Semantic proximity Read ↗

Interrelationships of VEL1 and ENV1 in light response and development in Trichoderma reesei.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.