Article
The Yin and Yang of linkage disequilibrium: mapping of genes and nucleotides conferring insecticide resistance in insect disease vectors.
Advances in experimental medicine and biology - 1 Jan 2008
Black William C, Gorrochetegui-Escalante Norma, Randle Nadine P, Donnelly Martin J
Abstract excerpt
Genetic technologies developed in the last 20 years have lead to novel and exciting methods to identify genes and specific nucleotides within genes that control phenotypes in field collected organisms. In this review we define and explain two of these methods: linkage disequilibrium (LD) mapping and quantitative trait nucleotide (QTN) mapping. The power to detect valid genotype-phenotype associations with LD or...
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