Article
Association mapping of insecticide resistance in wild Anopheles gambiae populations: major variants identified in a low-linkage disequilbrium genome.
PloS one - 1 Oct 2010
Weetman David, Wilding Craig S, Steen Keith, Morgan John C, Simard Frédéric, Donnelly Martin J
Abstract excerpt
BACKGROUND: Association studies are a promising way to uncover the genetic basis of complex traits in wild populations. Data on population stratification, linkage disequilibrium and distribution of variant effect-sizes for different trait-types are required to predict study success but are lacking for most taxa. We quantified and investigated the impacts of these key variables in a large-scale association study...
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