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Article

GPR56 regulates pial basement membrane integrity and cortical lamination.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 28 May 2008

Li Shihong, Jin Zhaohui, Koirala Samir, Bu Lihong, Xu Lei, Hynes Richard O, Walsh Christopher A, Corfas Gabriel, Piao Xianhua

Abstract excerpt

GPR56 is a member of the family of adhesion G-protein-coupled receptors that have a large extracellular region containing a GPS (G-protein proteolytic site) domain. Loss-of-function mutations in the GPR56 gene cause a specific human brain malformation called bilateral frontoparietal polymicrogyria (BFPP). BFPP is a radiological diagnosis and its histopathology remains unclear. This study demonstrates that loss of...

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Identifiers

PMID: 18509043
DOI: 10.1523/JNEUROSCI.0853-08.2008
PMCID: PMC2504715

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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