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Article

Anticancer activity of 3-demethylubiquinone Q2. In vivo experiments and probable mechanism of action.

Anticancer research - 1 Jan 2000

Fedorov Sergey N, Radchenko Oleg S, Shubina Larisa K, Balaneva Nadezda N, Agafonova Irina G, Bode Ann M, Jin Jun-O, Kwak Jong-Young, Dong Zigang, Stonik Valentin A

Abstract excerpt

BACKGROUND: 3-Demethylubiquinone Q2 (3DMUbQ2), isolated from the ascidian Aplidium glabrum and later synthesized, is known as a natural product inhibiting EGF-induced malignant JB6 P+ Cl 41 cell transformation. However, its in vivo anticancer properties and probable mechanism of this action have...

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PMID: 18507038

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EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18507038-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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