Article

An organic extract from ascidian <i>Ciona robusta</i> induces cytotoxic autophagy in human malignant cell lines

2023-11-18

Abstract excerpt

The last decades have seen an increase in the isolation and characterization of anticancer compounds derived from marine organisms, especially invertebrates, and their use in clinical trials. In this regard, ascidians, which are included in the subphylum Tunicata, represent successful examples with two drugs, Aplidine© and Yondelis©, that reached the market as orphan drugs against several malignancies. Here, we re...

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Literature Corpus work: eac21d31-6bcc-5ba9-a59a-7e5f9e5cd8c6
DOI: 10.1101/2023.11.18.567676

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