Article
Cancer risk in patients with constitutional chromosome deletions: a nationwide British cohort study.
British journal of cancer - 17 Jun 2008
Swerdlow A J, Schoemaker M J, Higgins C D, Wright A F, Jacobs P A
Abstract excerpt
The finding of increased risks of specific cancers in individuals with constitutional deletions of chromosomes 11p and 13q led to the discovery of cancer predisposition genes at these locations, but there have been no systematic studies of cancer risks in patients with constitutional deletions, across the chromosome complement. Therefore, we assessed cancer incidence in comparison with national cancer incidence...
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