Article
The polymorphism of XRCC3 codon 241 and AFB1-related hepatocellular carcinoma in Guangxi population, China.
Annals of epidemiology - 1 Jul 2008
Long Xi Dai, Ma Yun, Qu De Ying, Liu Yun Guang, Huang Zhao Quan, Huang Yong Zhi, Lin Zhong Hui, Wei Ni Bo, Zhou Shu Chun
Abstract excerpt
PURPOSE: The relationship between aflatoxin B1 (AFB1) exposure and hepatocellular carcinoma (HCC) has been previously demonstrated and supported with strong epidemiological evidence. However, the role of genetic polymorphism of X-ray cross-complementing group 3 (XRCC3) codon 241 (namely: Thr241Met), which may be involved in the repair of DNA double-strand breaks caused by carcinogens such as AFB1, been less well...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
