Article
alpha-Hemoglobin stabilizing protein is not a suitable marker for a screening test for variant Creutzfeldt-Jakob disease.
Transfusion - 1 Aug 2008
Appleford Nigel E J, Wilson Kim, Houston Fiona, Bruce Lesley J, Morrison Alex, Bishop Matthew, Chalmers Kevin, Miele Gino, Massey Edwin, Prowse Chris, Manson Jean, Will Robert G, Clinton Michael, MacGregor Ian, Anstee David J
Abstract excerpt
BACKGROUND: A test is needed to identify blood donors who are in the preclinical phase of variant Creutzfeldt-Jakob disease (CJD). alpha-Hemoglobin stabilizing protein (AHSP; syn. ERAF, EDRF) transcript levels are reduced in the blood of mice incubating transmissible spongiform encephalopathy. STUDY DESIGN AND METHODS: Quantitative real-time polymerase chain reaction and enzyme-linked immunosorbent assay were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.