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Article

Age-related cone abnormalities in zebrafish with genetic lesions in sonic hedgehog.

Investigative ophthalmology & visual science - 1 Oct 2008

Stenkamp Deborah L, Satterfield Rosanna, Muhunthan Kalyani, Sherpa Tshering, Vihtelic Thomas S, Cameron David A

Abstract excerpt

PURPOSE: Sonic hedgehog (Shh) signaling is essential for photoreceptor differentiation and retinal cell survival in embryonic zebrafish. The study was conducted to determine whether adult heterozygous carriers of mutant alleles for the shh gene display retinal abnormalities. METHODS: Retinal cryo...

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Share to Fluorescent Antibody Technique, Indirect
Share to Hedgehog Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18502998
DOI: 10.1167/iovs.07-1224
PMCID: PMC2584603

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18502998-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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