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Article

Leydig cell re-generation and expression of cell signaling molecules in the germ cell-free testis

23 May 2008

Abstract excerpt

Leydig cells in the rat testis can be specifically ablated with ethane dimethane sulfonate (EDS) and will subsequently re-generate. In this study, we have characterized Leydig cell re-generation and expression of selected cell-signaling molecules in a germ cell-free model of EDS action. This model offers the advantage that re-generation occurs on a stable background without confounding changes from the regressing...

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PMID: 18502897
DOI: 10.1530/rep-07-0529

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