Article
Circulating levels of mannan-binding lectin (MBL) and MBL-associated serine protease 2 in endemic pemphigus foliaceus.
Clinical and experimental dermatology - 1 Jul 2008
Messias-Reason I, Bosco D G, Nisihara R M, Jakobsen L H, Petzl-Erler M L, Jensenius J C
Abstract excerpt
Endemic pemphigus foliaceus (EPF) is an autoimmune disease, which occurs in Brazil and other regions of South America. Mannose-binding lectin (MBL) and MBL-associated serine protease (MASP-2) play a key role in innate immunity, and its deficiency has been related to increased susceptibility to infection and autoimmune diseases. MBL and MASP-2 serum levels were measured in 114 patients with EPF and in 100 healthy...
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