Osteogenesis imperfecta collagen-like peptides: self-assembly and mineralization on surfaces.

Abstract excerpt

Collagens constitute a large family of extracellar matrix proteins in humans and mammals that provide a structural framework for tissues. A number of hereditary connective tissue diseases are associated with mutations in collagens, including Osteogenesis imperfecta (OI). Collagen-like peptides were synthesized with alterations in primary sequence to represent native and mutation states related to this disease....

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