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Article

Estimation of 2Nes from temporal allele frequency data.

Genetics - 1 May 2008

Bollback Jonathan P, York Thomas L, Nielsen Rasmus

Abstract excerpt

We develop a new method for estimating effective population sizes, Ne, and selection coefficients, s, from time-series data of allele frequencies sampled from a single diallelic locus. The method is based on calculating transition probabilities, using a numerical solution of the diffusion process, and assuming independent binomial sampling from this diffusion process at each time point. We apply the method in two...

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Source

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Identifiers

PMID: 18493066
DOI: 10.1534/genetics.107.085019
PMCID: PMC2390626

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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