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Article

Gelsolin-related amyloidosis. Identification of the amyloid protein in Finnish hereditary amyloidosis as a fragment of variant gelsolin.

The Journal of clinical investigation - 1 Apr 1991

Maury C P

Abstract excerpt

The Finnish type of familial amyloidosis is a systemic disease characterized by progressive cranial neuropathy, corneal lattice dystrophy, and distal sensimotor neuropathy. Amyloid fibrils were isolated from the kidney and heart of a patient with Finnish amyloidosis. After solubilization, the amyloid proteins were fractionated by gel filtration and purified by reverse-phase HPLC. Complete amino acid sequence...

Topics

Amino Acid Sequence
Amyloidosis
Calcium-Binding Proteins
Finland
Gelsolin
Humans
Kidney
Microfilament Proteins
Molecular Sequence Data
Molecular Weight
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Peptide Fragments

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Identifiers

PMID: 1849145
DOI: 10.1172/JCI115118
PMCID: PMC295133

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1849145-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Gelsolin-related amyloidosis. Identification of the amyloid protein in Finnish hereditary amyloidosis as a fragment of variant gelsolin.PMID 1849145Read ↗

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