Article
Neurexin 1alpha structural variants associated with autism.
Neuroscience letters - 27 Jun 2008
Yan Jin, Noltner Katie, Feng Jinong, Li Wenyan, Schroer Richard, Skinner Cindy, Zeng Wenqi, Schwartz Charles E, Sommer Steve S
Abstract excerpt
Neurexins are presynaptic membrane cell-adhesion molecules which bind to neuroligins, a family of proteins that are associated with autism. To explore the possibility that structural variants in the neurexin alpha genes predispose to autism, the coding regions and associated splice junctions of the neurexin 1alpha gene were sequenced in 116 Caucasian patients with autism and 192 Caucasian controls. Five...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
