Article
Disruption of neurexin 1 associated with autism spectrum disorder.
American journal of human genetics - 1 Jan 2008
Kim Hyung-Goo, Kishikawa Shotaro, Higgins Anne W, Seong Ihn-Sik, Donovan Diana J, Shen Yiping, Lally Eric, Weiss Lauren A, Najm Juliane, Kutsche Kerstin, Descartes Maria, Holt Lynn, Braddock Stephen, Troxell Robin, Kaplan Lee, Volkmar Fred, Klin Ami, Tsatsanis Katherine, Harris David J, Noens Ilse, Pauls David L, Daly Mark J, MacDonald Marcy E, Morton Cynthia C, Quade Bradley J, Gusella James F
Abstract excerpt
Autism is a neurodevelopmental disorder of complex etiology in which genetic factors play a major role. We have implicated the neurexin 1 (NRXN1) gene in two independent subjects who display an autism spectrum disorder (ASD) in association with a balanced chromosomal abnormality involving 2p16.3....
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