Article
Analysis of hepatitis B virus genotype changes in patients with chronic hepatitis B infection on tenofovir therapy.
Journal of medical virology - 1 Aug 2016
Chauhan Ranjit, Singh Avishek K, Rooge Sheetalnath, Varshney Aditi, Kumar Manoj, Sarin Shiv K
Abstract excerpt
Antiviral therapy for chronic hepatitis B (CHB) is often required for prolonged periods. We investigated the instance of one HBV genotype switching to another during tenofovir therapy. Of the 67 patients, genotype A was present in 6 (8.9%), D in 43 (65.6%), C in 1 (1.5%), and mixed in 17 (23.8%) patients. Genotype changes were detected in 51 (76.1%) patients on therapy during a follow-up of 192 (range 52-312)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
