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Azathioprine treatment photosensitizes human skin to ultraviolet A radiation

16 May 2008

Abstract excerpt

BACKGROUND: Azathioprine is used to treat a variety of conditions and to prevent graft rejection in organ transplant recipients (OTRs). OBJECTIVES: To investigate clinically our previous finding that azathioprine metabolites interact with ultraviolet (UV) A radiation to form promutagenic oxidative DNA damage and to determine whether this may be causal or contributory to the development of excess skin cancers...

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Identifiers

PMID: 18489587
DOI: 10.1111/j.1365-2133.2008.08610.x

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