Article
Ultraviolet A radiation: its role in immunosuppression and carcinogenesis.
Seminars in cutaneous medicine and surgery - 1 Dec 2011
Halliday Gary M, Byrne Scott N, Damian Diona L
Abstract excerpt
Ultraviolet A (UVA) radiation is immunosuppressive and mutagenic in humans and carcinogenic in animals. UVA suppresses immunity with a bell-shaped dose response. At doses equivalent to 15-20 minutes of sun exposure at noon, UVA contributes to approximately 75% of sunlight-induced immunosuppression. A recent action spectrum, indicating that 360-380 nm but not 320-350 nm UVA suppresses immunity in humans, suggests...
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