Article
Smoking and the risk of breast cancer in BRCA1 and BRCA2 carriers: an update.
Breast cancer research and treatment - 1 Mar 2009
Ginsburg Ophira, Ghadirian Parviz, Lubinski Jan, Cybulski Cezary, Lynch Henry, Neuhausen Susan, Kim-Sing Charmaine, Robson Mark, Domchek Susan, Isaacs Claudine, Klijn Jan, Armel Susan, Foulkes William D, Tung Nadine, Moller Pal, Sun Ping, Narod Steven A
Abstract excerpt
Among women with a mutation in BRCA1 or BRCA2, the risk of breast cancer is high, but it may be modified by exogenous and endogenous factors. There is concern that exposure to carcinogens in cigarette smoke may increase the risk of cancer in mutation carriers. We conducted a matched case-control study of 2,538 cases of breast cancer among women with a BRCA1 (n = 1,920) or a BRCA2 (n = 618) mutation. One...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.