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Article

A second gene product of the inositol-phospholipid-specific phospholipase C delta subclass.

European journal of biochemistry - 26 Feb 1991

Meldrum E, Kriz R W, Totty N, Parker P J

Abstract excerpt

Sequence analysis of a inositol-phospholipid-specific phospholipase C (PtdIns-PLC) purified from bovine brain has led to the isolation of a novel cDNA that encodes this protein. While this cDNA contains two introns, these appear to be removed upon transfection of the cDNA into COS-1 cells. The protein transiently expressed in COS-1 cells shows phosphatidylinositol 4,5-bisphosphate hydrolysing activity which...

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PMID: 1848183
DOI: 10.1111/j.1432-1033.1991.tb15799.x

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