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Article

When good transcripts go bad: artifactual RT-PCR 'splicing' and genome analysis.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Jun 2008

Roy Scott William, Irimia Manuel

Abstract excerpt

Gene and intron prediction are essential for accurate inferences about genome evolution. Recently, two genome-wide studies searched for recent intron gains in humans, reaching very different conclusions: either of a complete absence of intron gain since early mammalian evolution, or of creation o...

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Share to DNA, Protozoan
Share to Gene Duplication
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Repetitive Sequences, Nucleic Acid

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Source

Identifiers

PMID: 18478540
DOI: 10.1002/bies.20749

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18478540-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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