Article
WNT SIGNALING IN PROSTATE DEVELOPMENT AND CARCINOGENESIS
1 Mar 2011
Abstract excerpt
BACKGROUND: The Wnt signaling pathway is crucial for cell fate decisions, stem cell renewal, regulation of cell proliferation and differentiation. Deregulated Wnt signaling is also implicated in a number of hereditary and degenerative diseases and cancer. METHODS AND RESULTS: This review highlights the role of the Wnt pathway in the regulation of stem/progenitor cell renewal and prostate gland development and how...
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