Article
Clinical, cytogenetic and molecular evaluation in a dog with bilateral cryptorchidism and hypospadias.
Cytogenetic and genome research - 1 Jan 2008
Cassata R, Iannuzzi A, Parma P, De Lorenzi L, Peretti V, Perucatti A, Iannuzzi L, Di Meo G P
Abstract excerpt
The aim of this study was to estimate prognostic factors in a Dalmatian dog with bilateral cryptorchidism and hypospadias. Cytogenetic and molecular analyses revealed a normal karyotype (2n = 78,XY) and the presence of SRY, INSL3 and RXFP2 genes with a normal DNA sequence for SRY and RXFP2, while the INSL3 sequence differed slightly from the normal one due to a heterozygous nucleotide change involving amino acid...
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