Article
Genomic Sequencing to Detect Cross-Breeding Quality in Dogs: An Example Studying Disorders in Sexual Development.
International journal of molecular sciences - 6 Oct 2024
de Gennaro Luciana, Burgio Matteo, Lacalandra Giovanni Michele, Petronella Francesco, L'Abbate Alberto, Ravasini Francesco, Trombetta Beniamino, Rizzo Annalisa, Ventura Mario, Cicirelli Vincenzo
Abstract excerpt
Disorders of sexual development (DSDs) in dogs, similar to humans, arise from genetic mutations, gonadal differentiation, or phenotypic sex development. The French Bulldog, a breed that has seen a surge in popularity and demand, has also shown a marked increase in DSD incidence. This study aims to characterize the genetic underpinnings of DSDs in a French Bulldog named Brutus, exhibiting ambiguous genitalia and...
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