Article
Activated protein C mediates a healing phenotype in cultured tenocytes.
Journal of cellular and molecular medicine - 1 Apr 2009
Xue Meilang, Smith Margaret M, Little Christopher B, Sambrook Philip, March Lyn, Jackson Christopher J
Abstract excerpt
Tendon injuries cause considerable morbidity in the general adult population. The tenocytes within the tendon have the full capacity to heal the tendon intrinsically. Activated protein C (APC) plays an important role in coagulation and inflammation and more recently has been shown to promote cutaneous wound healing. In this study we examined whether APC can induce a wound healing phenotype in tenocytes. Sheep...
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