Article
Genetic and environmental findings in early-onset Parkinson's disease Brazilian patients.
Movement disorders : official journal of the Movement Disorder Society - 15 Jul 2008
Aguiar Patricia de Carvalho, Lessa Patricia Silva, Godeiro Clecio, Barsottini Orlando, Felício Andre Carvalho, Borges Vanderci, Silva Sonia Maria de Azevedo, Saba Roberta Arb, Ferraz Henrique Ballalai, Moreira-Filho Carlos A, Andrade Luiz Augusto F
Abstract excerpt
Parkinson's disease (PD) etiology has been attributed both to genetic and environmental factors. In this study, we investigated Brazilian early-onset PD (EOPD) patients for mutations in PARK2 and PARK8, exposure to environmental factors and possible correlations between PARK2 polymorphisms, environmental exposure, and disease age of onset. We enrolled 72 EOPD index patients and 81 healthy volunteers. Both groups...
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