Article
A pilot genome-wide association study of early-onset breast cancer.
Breast cancer research and treatment - 1 Apr 2009
Kibriya Muhammad G, Jasmine Farzana, Argos Maria, Andrulis Irene L, John Esther M, Chang-Claude Jenny, Ahsan Habibul
Abstract excerpt
High-density oligonucleotide microarrays containing a large number of single nucleotide polymorphisms (SNPs) have enabled genome-wide association (GWA) analysis to become a reality. We used the early access Affymetrix Mendel Nsp 250K chips in a GWA case-control pilot study to identify genomic regions associated with breast cancer. We included 30 randomly sampled incident invasive breast cancer cases aged <45...
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