Mouse Leydig insulin-like (Ley I-L) gene: Structure and expression during testis and ovary development

Abstract excerpt

Leydig insulin-like protein (Ley I-L) is a novel member of the insulin-like hormone superfamily. We report here the isolation and expression of the mouse Ley I-L gene. The gene encodes a polypeptide of 122 amino acids that shows a relatively weak homology (54%) to human and porcine prepro-Ley I-L. However, the predicted B and A chain of the mature mouse Ley I-L exhibit similarities of 73% and 71% with human and...

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