Article
Mechanisms determining phenotypic heterogeneity of hepatocytes.
Biochemistry. Biokhimiia - 1 Apr 2008
Usynin I F, Panin L E
Abstract excerpt
This review summarizes results of biochemical and immunohistochemical studies indicating the existence of functional heterogeneity of hepatocytes depending on their localization in the hepatic acinus; this determines characteristic features of metabolism of carbohydrates, lipids, and xenobiotics. The physiological significance of hepatocyte heterogeneity is discussed. According to the proposed model of...
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