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Article

[Construction of FANCA mutant protein from Fanconi anemia patient and analysis of its function].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Nov 2007

Chen Fei, Zhang Ke-Jian, Zuo Xue-Lan, Zeng Xian-Chang

Abstract excerpt

OBJECTIVE: To study FANCA protein expression in Fanconi anemia patient's (FA) cells and explore its function. METHODS: FANCA protein expression was analyzed in 3 lymphoblast cell lines derived from 3 cases of type A FA (FA-A) patients using Western blot. Nucleus and cytoplasm localization of FANCA protein was analyzed in one case of FA-A which contained a truncated FANCA (exon 5 deletion). The FANCA mutant was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18457264

Genes

FANCA
FANCG

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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