Article
Analysis of the contribution of molecular mechanisms into formation of gonoccocal resistance to tetracycline.
Bulletin of experimental biology and medicine - 1 Sept 2007
Borovskaya A D, Malakhova M V, Vereshchagin V A, Il'ina E N, Govorun V M, Priputnevich T V, Al-Hafagi N, Kubanova A A
Abstract excerpt
We applied complex genetic analysis for evaluation of tetracycline-resistance markers in 129 clinical strains of Neisseria gonorrhoeae from Central, Privolzhskii, and Siberian regions. For detection of mutations in rpsJ gene and MtrRCDE locus we first used minisequence reaction followed by identification of products by MALDI-TOF mass spectrometry. The incidence of detection of resistance markers among the...
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