Article
Direct evaluation of drug resistance parameters in gonococcus.
Bulletin of experimental biology and medicine - 1 Aug 2007
Il'ina E N, Malakhova M V, Vereshchagin V A, Govorun V M, Priputnevich T V, Kubanova A A
Abstract excerpt
We carried out complex genetic analysis of clinical samples containing N. gonorrhoeae DNA, the genotype and profile of drug resistance of this agent were evaluated. Changes in genes responsible for the formation of N. gonorrhoeae resistance to penicillins, fluoroquinolones, and spectinomycin were detected during minisequencing with subsequent MALDI-TOF mass spectrometry. The sensitivity of gonococcus was...
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