Direct evaluation of drug resistance parameters in gonococcus.

doi:10.1007/s10517-007-0296-3

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Article

Direct evaluation of drug resistance parameters in gonococcus.

Bulletin of experimental biology and medicine - 1 Aug 2007

Il'ina E N, Malakhova M V, Vereshchagin V A, Govorun V M, Priputnevich T V, Kubanova A A

Abstract excerpt

We carried out complex genetic analysis of clinical samples containing N. gonorrhoeae DNA, the genotype and profile of drug resistance of this agent were evaluated. Changes in genes responsible for the formation of N. gonorrhoeae resistance to penicillins, fluoroquinolones, and spectinomycin were detected during minisequencing with subsequent MALDI-TOF mass spectrometry. The sensitivity of gonococcus was...

Topics

DNA, Bacterial
Drug Resistance, Bacterial
Female
Fluoroquinolones
Genes, Bacterial
Gonorrhea
Humans
Male
Microbial Sensitivity Tests
Mutation
Neisseria gonorrhoeae
Penicillin Resistance
Sequence Analysis, DNA
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Source

Open in PubMed

Identifiers

PMID: 18399287
DOI: 10.1007/s10517-007-0296-3

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