Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

YscU cleavage and the assembly of Yersinia type III secretion machine complexes.

Molecular microbiology - 1 Jun 2008

Riordan Kelly E, Schneewind Olaf

Abstract excerpt

YscU, a component of the Yersinia type III secretion machine, promotes auto-cleavage at asparagine 263 (N263). Mutants with an alanine substitution at yscU codon 263 displayed secretion defects for some substrates (LcrV, YopB and YopD); however, transport of effector proteins into host cells (YopE, YopH, YopM) continued to occur. Two yscU mutations were isolated that, unlike N263A, completely abolished type III...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Gene Expression Regulation, Bacterial
Share to HeLa Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Protein Binding

Share to Protein Isoforms

Share to Protein Processing, Post-Translational

Share to Protein Transport

Share to Yersinia

Source

Open in PubMed Open full text

Identifiers

PMID: 18452514
DOI: 10.1111/j.1365-2958.2008.06247.x
PMCID: PMC3538813

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

YscU cleavage and the assembly of Yersinia type III secretion machine complexes.PMID 18452514Read ↗

Autoproteolysis of YscU of Yersinia pseudotuberculosis is important for regulation of expression and secretion of Yop proteins.Semantic proximity Read ↗

Autoproteolysis and intramolecular dissociation of Yersinia YscU precedes secretion of its C-terminal polypeptide YscU(CC).Semantic proximity Read ↗

Impassable YscP substrates and their impact on the Yersinia enterocolitica type III secretion pathway.Semantic proximity Read ↗

YscP and YscU regulate substrate specificity of the Yersinia type III secretion system.Semantic proximity Read ↗

YscP and YscU switch the substrate specificity of the Yersinia type III secretion system by regulating export of the inner rod protein YscI.Semantic proximity Read ↗

Identification of SycN, YscX, and YscY, three new elements of the Yersinia yop virulon.Semantic proximity Read ↗

YscU recognizes translocators as export substrates of the Yersinia injectisome.Semantic proximity Read ↗

The YscE/YscG chaperone and YscF N-terminal sequences target YscF to the Yersinia pestis type III secretion apparatus.Semantic proximity Read ↗

YopD self-assembly and binding to LcrV facilitate type III secretion activity by Yersinia pseudotuberculosis.Semantic proximity Read ↗

Atomic resolution structure of the cytoplasmic domain of Yersinia pestis YscU, a regulatory switch involved in type III secretion.Semantic proximity Read ↗

Yersinia pestis YscG protein is a Syc-like chaperone that directly binds yscE.Semantic proximity Read ↗

An amino-terminal secretion signal is required for YplA export by the Ysa, Ysc, and flagellar type III secretion systems of Yersinia enterocolitica biovar 1B.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.