Article
The neuronal ubiquitin-proteasome system: murine models and their neurological phenotype.
Progress in neurobiology - 1 Jun 2008
van Tijn Paula, Hol Elly M, van Leeuwen Fred W, Fischer David F
Abstract excerpt
The ubiquitin-proteasome system (UPS) is the main intracellular pathway for regulated protein turnover. This system is of vital importance for maintaining cellular homeostasis and is essential for neuronal functioning. It is therefore not surprising that impairment of this system is implicated in...
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