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Article

Intracardiac septation requires hedgehog-dependent cellular contributions from outside the heart.

Development (Cambridge, England) - 1 May 2008

Goddeeris Matthew M, Rho Silvia, Petiet Alexandra, Davenport Chandra L, Johnson G Allan, Meyers Erik N, Klingensmith John

Abstract excerpt

Septation of the mammalian heart into four chambers requires the orchestration of multiple tissue progenitors. Abnormalities in this process can result in potentially fatal atrioventricular septation defects (AVSD). The contribution of extracardiac cells to atrial septation has recently been recognized. Here, we use a genetic marker and novel magnetic resonance microscopy techniques to demonstrate the origins of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18441277
DOI: 10.1242/dev.016147
PMCID: PMC2746050

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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