An apolipoprotein A-V gene SNP is associated with marked hypertriglyceridemia among Asian-American patients.

doi:10.1194/jlr.P800011-JLR200

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

An apolipoprotein A-V gene SNP is associated with marked hypertriglyceridemia among Asian-American patients.

Journal of lipid research - 1 Aug 2008

Pullinger Clive R, Aouizerat Bradley E, Movsesyan Irina, Durlach Vincent, Sijbrands Eric J, Nakajima Katsuyuki, Poon Annie, Dallinga-Thie Geesje M, Hattori Hiroaki, Green Lauri L, Kwok Pui-Yan, Havel Richard J, Frost Philip H, Malloy Mary J, Kane John P

Abstract excerpt

Apolipoprotein A-V (apoA-V) is an important regulator of plasma levels of triglyceride (TG) in mice. In humans, APOA5 genetic variation is associated with TG in several populations. In this study, we determined the effects of the p.185Gly>Cys (c.553G>T; rs2075291) polymorphism on plasma TG levels in subjects of Chinese ancestry living in the United States and in a group of non-Chinese Asian ancestry. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoprotein A-V

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apolipoproteins A

Share to Asian

Share to Asian People

Share to China

Share to Gene Frequency

Share to Haplotypes

Share to Hypertriglyceridemia

Source

Open in PubMed Open full text

Identifiers

PMID: 18441017
DOI: 10.1194/jlr.P800011-JLR200
PMCID: PMC2444008

Genes

APOA5

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An apolipoprotein A-V gene SNP is associated with marked hypertriglyceridemia among Asian-American patients.PMID 18441017Read ↗

APOA5 Ala315>Val, identified in patients with severe hypertriglyceridemia, is a common mutation with no major effects on plasma lipid levels.Semantic proximity Read ↗

APOA5-1131T>C polymorphism is associated with triglyceride levels in Chinese men.Semantic proximity Read ↗

Relative contribution of variation within the APOC3/A4/A5 gene cluster in determining plasma triglycerides.Semantic proximity Read ↗

Apoprotein A-V: an important regulator of triglyceride metabolism.Semantic proximity Read ↗

Apolipoprotein A5 and triglyceridemia. Focus on the effects of the common variantsSemantic proximity Read ↗

A triglyceride-raising APOA5 genetic variant is negatively associated with obesity and BMI in the Chinese population.Semantic proximity Read ↗

Genetic determinants of plasma triglycerides.Semantic proximity Read ↗

The c.553G>T Genetic Variant of the APOA5 Gene and Altered Triglyceride Levels in the Asian Population: A Meta-Analysis of Case-Control Studies.Semantic proximity Read ↗

Genetic variation in apolipoprotein A-V in hypertriglyceridemia.Semantic proximity Read ↗

Update on APOA5 Genetics: Toward a Better Understanding of Its Physiological Impact.Semantic proximity Read ↗

A genetic variant c.553G > T in the apolipoprotein A5 gene is associated with an increased risk of coronary artery disease and altered triglyceride levels in a Chinese population.Semantic proximity Read ↗

A functional variant in APOA5/A4/C3/A1 gene cluster contributes to elevated triglycerides and severity of CAD by interfering with microRNA 3201 binding efficiency.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.