Article
Mitochondrial membrane potential in human neutrophils is maintained by complex III activity in the absence of supercomplex organisation.
PloS one - 23 Apr 2008
van Raam Bram J, Sluiter Wim, de Wit Elly, Roos Dirk, Verhoeven Arthur J, Kuijpers Taco W
Abstract excerpt
BACKGROUND: Neutrophils depend mainly on glycolysis for their energy provision. Their mitochondria maintain a membrane potential (Deltapsi(m)), which is usually generated by the respiratory chain complexes. We investigated the source of Deltapsi(m) in neutrophils, as compared to peripheral blood mononuclear leukocytes and HL-60 cells, and whether neutrophils can still utilise this Deltapsi(m) for the generation...
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