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Article

Glutathione S-transferase A1 polymorphism as a risk factor for smoking-related type 2 diabetes among Japanese.

Toxicology letters - 30 May 2008

Oniki Kentaro, Umemoto Yuichiro, Nagata Rie, Hori Masaharu, Mihara Shuichi, Marubayashi Toru, Nakagawa Kazuko

Abstract excerpt

Glutathione S-transferases protect cells against exogenous and endogenous oxidative stress. Type 2 diabetes is associated with an increased production of reactive oxygen species and a reduction in antioxidant defenses. This study investigated whether GSTA1*A/*B and GSTP1Ile105Val polymorphisms could affect the risk for type 2 diabetes. A cross-sectional case-control analysis included 468 (326 men and 142 women)...

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Source

Identifiers

PMID: 18430527
DOI: 10.1016/j.toxlet.2008.03.004

Genes

GSTA1
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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