Article
Glutathione S-Transferase Pi-Ile 105 Val Polymorphism and Susceptibility to T2DM in Population from Turabah Region of Saudi Arabia.
Biochemical genetics - 1 Aug 2016
Mergani Adil, Mansour Ahmed Abdelkhalik, Askar Tamer, Zahran Rasha Nabeel, Mustafa Adil Musa, Mohammed Mukhtar Ahmed, Saleh Osama Mosailhy
Abstract excerpt
Type 2 diabetes mellitus is characterized by chronic hyperglycemia and associated with oxidative stress resulting from accumulation of free radicals in body's tissues, which especially affects beta cells in pancreas and is an important factor in the development of diabetes and its complications. Glutathione S-transferases (GSTs) are a family of antioxidant enzymes that play important roles in decreasing ROS...
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