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Article

Human platelet antigen 1-6, 9 and 15 in the Iranian population: An anthropological genetic analysis.

Scientific reports - 4 May 2020

Kazemi Mohammad Hossein, Malakootikhah Farideh, Momeni-Varposhti Zahra, Falak Reza, Delbandi Ali-Akbar, Tajik Nader

Abstract excerpt

Human platelet antigens (HPAs) are membranous glycoproteins considered as alloantigens due to their polymorphisms. HPA-incompatibility in multiple pregnancies or blood transfusion can induce the development of alloantibodies leading to thrombocytopenia. The frequency of HPAs varies among populations, so that deep knowledge of HPA frequencies will help us to reduce those incompatibilities. Herein, we studied the...

Topics

Alleles
Antigens, Human Platelet
Blood Donors
Blood Platelet Disorders
Cluster Analysis
Gene Frequency
Genetic Testing
Genetics, Population
Genotype
Haplotypes
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Iran

Isoantibodies

Isoantigens

Polymorphism, Genetic

Thrombocytopenia

Source

Open in PubMed Open full text

Identifiers

PMID: 32366900
DOI: 10.1038/s41598-020-64469-4
PMCID: PMC7198494

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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