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Article

Beta-tropomyosin mutations alter tropomyosin isoform composition.

European journal of neurology - 1 Jun 2008

Nilsson J, Tajsharghi H

Abstract excerpt

BACKGROUND AND PURPOSE: Tropomyosin (TM) is an actin-binding protein, which is localized head to tail along the length of the actin filament. There are three major TM isoforms in human striated muscle. Mutations in beta-tropomyosin (TPM2) have recently been identified as an important cause of neuromuscular disorders. MATERIALS AND METHODS: The expression of TM isoforms in patients carrying mutations in TPM2 was...

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Share to Electrophoresis, Polyacrylamide Gel
Share to Immunohistochemistry

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Muscle, Skeletal

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Share to Reverse Transcriptase Polymerase Chain Reaction

Share to Sequence Analysis, Protein

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Source

Identifiers

PMID: 18422639
DOI: 10.1111/j.1468-1331.2008.02131.x

Genes

TPM2
SDS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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