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Complete genome sequence analysis of Seneca Valley virus-001, a novel oncolytic picornavirus

17 Apr 2008

Abstract excerpt

The complete genome sequence of Seneca Valley virus-001 (SVV-001), a small RNA virus, was determined and was shown to have typical picornavirus features. The 7280 nt long genome was predicted to contain a 5' untranslated region (UTR) of 666 nt, followed by a single long open reading frame consisting of 6543 nt, which encodes a 2181 aa polyprotein. This polyprotein could potentially be cleaved into 12 polypeptides...

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PMID: 18420805
DOI: 10.1099/vir.0.83570-0

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