Article
Molecular analysis of sleep: wake cycles in Drosophila.
Cold Spring Harbor symposia on quantitative biology - 1 Jan 2007
Sehgal A, Joiner W, Crocker A, Koh K, Sathyanarayanan S, Fang Y, Wu M, Williams J A, Zheng X
Abstract excerpt
Sleep is controlled by two major regulatory systems: a circadian system that drives it with a 24-hour periodicity and a home-ostatic system that ensures that adequate amounts of sleep are obtained. We are using the fruit fly Drosophila melanogaster to understand both types of regulation. With respect to circadian control, we have identified molecular mechanisms that are critical for the generation of a clock. Our...
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